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Evidence-Based Medicine

Step 2 Acquire the Best Evidence: Where Evidence Meets Understanding

Learn how to acquire the best available evidence efficiently in step 2 of evidence-based medicine. Learn why this matters so that you can master the how.

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In this episode of This Is Why, Dr. Busti continues the deep dive into Evidence-Based Medicine, focusing on the second “A” — Acquire. Learn how to efficiently search for and identify the best available evidence using PICO, Boolean logic, and major databases like TRIP, PubMed, and Cochrane.

This session builds directly on Step 1 (“Ask”) and shows practical search strategies to refine your clinical questions, recognize differences between primary, secondary, and tertiary literature sources, and balance search sensitivity vs. specificity to find relevant, trustworthy evidence faster.

Disclaimer:
This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this content.

TOC

00:00 – Introduction: Why understanding the “why” matters
02:10 – Step 1 Recap: Asking the right clinical question
06:00 – Step 2: Acquiring evidence effectively
10:45 – Understanding primary, secondary & tertiary sources
17:25 – Search strategy essentials: Boolean logic & filters
25:10 – Clinical example: Statins in primary prevention
32:20 – Practical takeaways & closing thoughts

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Dive Deeper

Bonus Video (ad free)

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Downloads

EBM Step 2 Tables and Graphics

Dive Deeper

Bonus Video

Downloads

EBM Step 2 Tables and Graphics