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Evidence-Based Medicine

EBM Step 2: Acquire the Best Evidence - Made Easy & Relevant

Learn how to acquire the best available evidence efficiently in step 2 of evidence-based medicine (EBM). Learn why this matters so that you can master the how.

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In this episode of This Is Why, Dr. Busti continues the deep dive into Evidence-Based Medicine (EBM), focusing on the second “A” in the 5 As of EBM — Acquire the best evidence. Learn how to efficiently search for and identify the best available evidence using PICO, Boolean logic, and major databases like TRIP, PubMed, and Cochrane. The goal "EBM" Made Easy".

This session builds directly on Step 1 of EBM (“Ask”) and shows practical search strategies to refine your clinical questions, recognize differences between primary, secondary, and tertiary literature sources, and balance search sensitivity vs. specificity to find relevant, trustworthy evidence faster.

Chapters

00:00 – Introduction: Why understanding the “why” matters
01:20 – EBM Step 1 Recap: Asking the right clinical question
03:08 – EBM Step 2: Acquiring the best evidence effectively
13:07 – Understanding primary, secondary & tertiary sources
15:09 – Search strategy essentials: Boolean logic & filters
27:25 – Clinical example: Statins in primary prevention
37:30 – Practical takeaways & closing thoughts


#evidencebasedmedicinecourse #ebmmadeeasy #5AsofEBM #ebm #evidencebasedmedicine #evidencebasedpractice

Speaker:

Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, is a licensed healthcare professional and medical educator with over 30 years of experience in clinical practice and academic teaching. He has trained and practiced as a nurse, pharmacist, and physician, bringing a uniquely comprehensive perspective to patient care and medical education.

Dr. Busti is dedicated to advancing evidence-based medicine and helping clinicians understand the underlying “why” behind clinical decisions to improve patient outcomes.


About This Channel:

This content is created by Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, a board-certified physician with training at Johns Hopkins School of Medicine and University of Oxford and a medical educator for healthcare professionals and students. All material is based on current medical literature and evidence-based guidelines that align with principles of evidence-based medicine (EBM) and Evidence-Based Healthcare (EBHC).


Disclaimer:

This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

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Downloads

EBM Step 2 Tables and Graphics

Dive Deeper

Bonus Video

Downloads

EBM Step 2 Tables and Graphics