Follow bile from hepatic production through gallbladder storage, concentration, and meal-triggered release. Learn how cholecystokinin coordinates delivery, how the cystic duct connects the gallbladder to the common bile duct, and why stone location changes the clinical consequences.

Apply this framework to cholelithiasis, cholecystitis, choledocholithiasis, cholangitis, and gallstone pancreatitis. The lecture connects structure and function to bedside findings and explains why stones alone do not establish acute gallbladder inflammation.

Compare the questions answered by gallbladder ultrasound, MRCP, and a HIDA scan, including the limitations of interpreting gallbladder ejection fraction. You will also learn why bile production continues after cholecystectomy. Anatomical illustrations, ultrasound examples, and a rotating 3D MRCP reconstruction help connect the concepts to clinical interpretation.

When we understand the why, we improve the how.

Chapter Table of Contents
00:00 - Introduction
03:30 - Bile Production & the Biliary System
07:30 - Gallbladder Anatomy & Structure
12:00 - How the Gallbladder Stores & Concentrates Bile
16:30 - Bile Release, CCK, & the Sphincter of Oddi
21:00 - Gallstones & Biliary Obstruction
26:00 - Gallbladder Disorders & Clinical Symptoms
31:00 - Ultrasound, HIDA Scan, MRCP, & ERCP
35:48 - Why You Can Live Without a Gallbladder
37:29 - Six Key Takeaways & Clinical Applications

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Speaker:
Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, is a licensed healthcare professional and medical educator with over 30 years of experience in clinical practice and academic teaching. He has trained and practiced as a nurse, pharmacist, and physician, bringing a uniquely comprehensive perspective to patient care and medical education.
Dr. Busti is dedicated to advancing evidence-based medicine and helping clinicians understand the underlying “why” behind clinical decisions to improve patient outcomes.

About This Channel:
This content is created by Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, a board-certified physician with training at Johns Hopkins School of Medicine and University of Oxford and a medical educator for healthcare professionals and students. All material is based on current medical literature and evidence-based guidelines aligned with the principles of evidence-based medicine (EBM) and Evidence-Based Healthcare (EBHC).

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.